Inhibition of human B-cell development into plasmablasts by histone deacetylase inhibitor valproic acid

In particular, VPA ameliorates the pathogenesis of experimental autoimmune encephalomyelitis,E1 decreases the incidence and severity of collagen-induced arthritis,E2 and attenuates inflammation in autoimmune neuritis.E3In vitro treatment of human dendritic cells with VPA impairs their migratory capa...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2013-06, Vol.131 (6), p.1695-1699.e9
Hauptverfasser:	Kienzler, Anne-Kathrin, MSc, Rizzi, Marta, MD, PhD, Reith, Maike, MSc, Nutt, Stephen L., PhD, Eibel, Hermann, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Antigens B-Lymphocytes - drug effects B-Lymphocytes - metabolism Cell Dedifferentiation - drug effects Cell Proliferation - drug effects Cell Survival - drug effects Histone Deacetylase Inhibitors - pharmacology Humans Immune system Immunoglobulins Immunophenotyping Kinases Phenotype Rodents Valproic Acid - pharmacology
Online-Zugang:	Volltext
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