Synthesis and Antioxidant Activity of a Variety of Sulfonamidomethane Linked 1,3,4-Oxadiazoles and Thiadiazoles

A variety of sulfonamidomethane linked 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were prepared and tested for antioxidant activity. The methyl substituted arylsulfonylaminomethyl-1,3,4-oxadiazole 9b showed excellent antioxidant activity.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical & pharmaceutical bulletin 2013/06/01, Vol.61(6), pp.611-617
Hauptverfasser:	Swapna, Mukkara, Premakumari, Chokkappagari, Reddy, Sanapalli Nagi, Padmaja, Adivireddy, Padmavathi, Venkatapuram
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3,4-oxadiazole 1,3,4-thiadiazole antioxidant activity Antioxidants - chemical synthesis Antioxidants - chemistry Hydrogen Peroxide - chemistry Nitric Oxide - chemistry Oxadiazoles - chemical synthesis Oxadiazoles - chemistry Oxidation-Reduction phosphorous oxychloride Sulfonamides - chemistry Thiadiazoles - chemical synthesis Thiadiazoles - chemistry thiourea
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Beschreibung
Zusammenfassung:	A variety of sulfonamidomethane linked 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were prepared and tested for antioxidant activity. The methyl substituted arylsulfonylaminomethyl-1,3,4-oxadiazole 9b showed excellent antioxidant activity.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.c12-00997