Rare, germline mutation of KIT with imatinib-resistant multiple GI stromal tumors and mastocytosis

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical oncology 2013-06, Vol.31 (16), p.e245-e247
Hauptverfasser:	Speight, Richard A, Nicolle, Annette, Needham, Stephanie J, Verrill, Mark W, Bryon, Jane, Panter, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Agents - pharmacology Benzamides - pharmacology Biomarkers, Tumor - analysis Drug Resistance, Neoplasm Exons Gastrointestinal Neoplasms - complications Gastrointestinal Neoplasms - diagnostic imaging Gastrointestinal Neoplasms - drug therapy Gastrointestinal Neoplasms - genetics Gastrointestinal Neoplasms - surgery Gastrointestinal Stromal Tumors - complications Gastrointestinal Stromal Tumors - diagnostic imaging Gastrointestinal Stromal Tumors - drug therapy Gastrointestinal Stromal Tumors - genetics Gastrointestinal Stromal Tumors - surgery Germ-Line Mutation Humans Imatinib Mesylate Immunohistochemistry Intestine, Small - pathology Intestine, Small - surgery Male Mastocytosis - complications Mastocytosis - genetics Piperazines - pharmacology Protein Kinase Inhibitors - pharmacology Proto-Oncogene Proteins c-kit - analysis Proto-Oncogene Proteins c-kit - genetics Pyrimidines - pharmacology Tomography, X-Ray Computed
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