Asymmetric synthesis of gem-diaryl substituted cyclic sulfamidates and sulfamides by rhodium-catalyzed arylation of cyclic ketimines

Asymmetric addition of arylboronates to aryl-substituted cyclic ketimines proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of sulfamidates and sulfamides with high enantioselectivity (up to 99% ee).

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (48), p.5504-5506
Hauptverfasser:	Nishimura, Takahiro, Ebe, Yusuke, Fujimoto, Hiroto, Hayashi, Tamio
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - chemical synthesis Amides - chemistry Boronic Acids - chemistry Catalysis Cyclization Imines - chemical synthesis Imines - chemistry Nitriles - chemical synthesis Nitriles - chemistry Rhodium - chemistry Stereoisomerism Sulfonic Acids - chemical synthesis Sulfonic Acids - chemistry
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Beschreibung
Zusammenfassung:	Asymmetric addition of arylboronates to aryl-substituted cyclic ketimines proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of sulfamidates and sulfamides with high enantioselectivity (up to 99% ee).
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c3cc42071j