IL-6 Genotype of Hematopoietic Stem Cells

IL-6 Genotype of Hematopoietic Stem Cells

[...]some investigators addressed the transcribed DNA strand2 while others studied the antiparallel strand,3-5 or simply failed to specify which strand they amplified.6,7 However, unless this information is taken into account, there is no way of telling whether the at-risk allele was "G,"...

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Veröffentlicht in:Clinical therapeutics 2013-05, Vol.35 (5), p.744-744
1. Verfasser: Sand, Philipp G., MD
Format: Artikel
Sprache:eng
Schlagworte:
Bone marrow
Genetic Predisposition to Disease
Genotype & phenotype
Graft vs Host Disease - genetics
Humans
Interleukin-6 - genetics
Internal Medicine
Medical Education
Polymorphism, Genetic
Stem cells
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Zusammenfassung:[...]some investigators addressed the transcribed DNA strand2 while others studied the antiparallel strand,3-5 or simply failed to specify which strand they amplified.6,7 However, unless this information is taken into account, there is no way of telling whether the at-risk allele was "G," or rather "C," as rs1800795 stands for a canonical G:
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2013.03.012