Elucidating absolute configuration of unsaturated alcohols via enantioselective acylation reactions

Enantioselective nucleophilic acylation catalysis provides a simple method of determining absolute configuration for unsaturated alcohols. Extension of this technique to natural products and synthetic compounds, as well as current limitations of this approach, are also described.

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Veröffentlicht in:Organic & biomolecular chemistry 2013-06, Vol.11 (21), p.3432-3435
Hauptverfasser: LeGay, Christina M, Boudreau, Colton G, Derksen, Darren J
Format: Artikel
Sprache:eng
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Zusammenfassung:Enantioselective nucleophilic acylation catalysis provides a simple method of determining absolute configuration for unsaturated alcohols. Extension of this technique to natural products and synthetic compounds, as well as current limitations of this approach, are also described.
ISSN:1477-0520
1477-0539
DOI:10.1039/c3ob40709h