Early Onset of Reproductive Function in Female Rats Treated with a High-Fat Diet

Puberty onset in mammals is tightly coupled to the animal’s nutritional and metabolic state. In the present study, we evaluated the effects of a high-fat diet on leptin and adiponectin levels, leptin mRNA expression and puberty onset in female rats. On day 21, female rats were divided into 2 groups,...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2013, Vol.75(4), pp.523-526
Hauptverfasser:	FUNGFUANG, Wirasak, NAKAO, Nobuhiko, NAKADA, Tomoaki, YOKOSUKA, Makoto, SAITO, Toru R.
Format:	Artikel
Sprache:	eng
Schlagworte:	adiponectin Adiponectin - blood Adiponectin - genetics Adiponectin - metabolism Animals Body Weight - physiology Dietary Fats - administration & dosage Dietary Fats - metabolism Eating - physiology Female female rats high-fat diet leptin Leptin - blood Leptin - genetics Leptin - metabolism leptin mRNA Rats Rats, Wistar Real-Time Polymerase Chain Reaction RNA, Messenger - chemistry RNA, Messenger - genetics Sexual Maturation - physiology
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Beschreibung
Zusammenfassung:	Puberty onset in mammals is tightly coupled to the animal’s nutritional and metabolic state. In the present study, we evaluated the effects of a high-fat diet on leptin and adiponectin levels, leptin mRNA expression and puberty onset in female rats. On day 21, female rats were divided into 2 groups, normal food (NF) and high-fat food (HF). The HF group showed a significantly earlier (P
ISSN:	0916-7250 1347-7439
DOI:	10.1292/jvms.12-0276