Effects of different modes of exercise on appetite and appetite-regulating hormones

► Rope skipping and bicycle ergometer exercise induced suppression of appetite. ► Ghrelin was suppressed and PYY was increased during both exercises. ► Appetite was suppressed to a greater extent with rope skipping than with cycling. ► The responses of ghrelin and PYY to rope skipping and cycling did not differ. The present study determined the changes in appetite and appetite-regulating gut hormones during and following bouts of both rope skipping exercise (weight-bearing) and bicycle ergometer exercise (non-weight-bearing). After a 12-h fast, 15 young men (mean±SD, age 24.4±1.7yrs, maximal oxygen uptake 47.0±6.5mL/kg/min) participated in three 160min trials: (1) rope skipping exercise (295±40kcal, 3 sets×10min with 5-min interval, then rested for 120min); (2) bicycle ergometer exercise (288±36kcal, 3 sets×10min with 5-min interval, then rested for 120min); (3) control (rested for 160min). Ratings of perceived hunger and acylated ghrelin were suppressed and total peptide YY (PYY) were increased during and immediately after exercise in both exercise trials, but glucagon liked peptide-1 was not changed. Furthermore, suppressed hunger during rope skipping exercise was greater than that during bicycle ergometer exercise, but there were no differences in acylated ghrelin and total PYY. These results indicate that weight-bearing exercise has a greater exercise-induced appetite suppressive effect compared with non-weight-bearing exercise, and both forms of exercise lowered acylated ghrelin and increased total PYY, but the changes did not differ significantly between exercise modes.