Recombinant Erdr1 suppresses the migration and invasion ability of human gastric cancer cells, SNU-216, through the JNK pathway
Highlights ► We investigate the effect of rErdr1 on gastric cancer cell. ► rErdr1 suppressed the migration and invasion ability of gastric cancer cell. ► rErdr1 treatment induced E-cadherin expression. ► rErdr1 suppressed the motility of gastric cancer through the activation of JNK pathway. ► rErdr1...
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Veröffentlicht in: | Immunology letters 2013-02, Vol.150 (1), p.145-151 |
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Hauptverfasser: | , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Highlights ► We investigate the effect of rErdr1 on gastric cancer cell. ► rErdr1 suppressed the migration and invasion ability of gastric cancer cell. ► rErdr1 treatment induced E-cadherin expression. ► rErdr1 suppressed the motility of gastric cancer through the activation of JNK pathway. ► rErdr1 may be suggesting therapeutic target for gastric cancer by inhibiting motility. |
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ISSN: | 0165-2478 1879-0542 |
DOI: | 10.1016/j.imlet.2013.01.012 |