Recombinant Erdr1 suppresses the migration and invasion ability of human gastric cancer cells, SNU-216, through the JNK pathway

Highlights ► We investigate the effect of rErdr1 on gastric cancer cell. ► rErdr1 suppressed the migration and invasion ability of gastric cancer cell. ► rErdr1 treatment induced E-cadherin expression. ► rErdr1 suppressed the motility of gastric cancer through the activation of JNK pathway. ► rErdr1...

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Veröffentlicht in:Immunology letters 2013-02, Vol.150 (1), p.145-151
Hauptverfasser: Jung, Min Kyung, Houh, Youn Kyung, Ha, Soogyeong, Yang, Yoolhee, Kim, Daejin, Kim, Tae Sung, Yoon, Suk Ran, Bang, Sa Ik, Cho, Byung Joo, Lee, Wang Jae, Park, Hyunjeong, Cho, Daeho
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Sprache:eng
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Zusammenfassung:Highlights ► We investigate the effect of rErdr1 on gastric cancer cell. ► rErdr1 suppressed the migration and invasion ability of gastric cancer cell. ► rErdr1 treatment induced E-cadherin expression. ► rErdr1 suppressed the motility of gastric cancer through the activation of JNK pathway. ► rErdr1 may be suggesting therapeutic target for gastric cancer by inhibiting motility.
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2013.01.012