Efficacy of combined antiviral therapy with lamivudine and tenofovir in a liver transplanted girl with de novo hepatitis B virus infection

The management of de novo hepatitis B (HBV) infection in children after liver transplantation is not well defined. Because this infection may induce severe liver disease in the graft liver, an efficient antiviral therapy is desirable. Here, we describe the favorable viral outcome observed in a liver...

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Veröffentlicht in:	Transplant infectious disease 2013-04, Vol.15 (2), p.E81-E84
Hauptverfasser:	Tufano, M., Liccardo, D., Riva, S., Candusso, M., Torre, G., Iorio, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - therapeutic use Antiviral Agents - therapeutic use Child, Preschool children combined antiviral therapy de novo HBV infection Drug therapy Drug Therapy, Combination Female Hepatitis hepatitis B Hepatitis B - drug therapy Hepatitis B virus Hepatitis B virus - isolation & purification Humans Infections lamivudine Lamivudine - therapeutic use Liver Transplantation Organophosphonates - therapeutic use Tenofovir Treatment Outcome
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Zusammenfassung:	The management of de novo hepatitis B (HBV) infection in children after liver transplantation is not well defined. Because this infection may induce severe liver disease in the graft liver, an efficient antiviral therapy is desirable. Here, we describe the favorable viral outcome observed in a liver transplanted girl with de novo HBV infection following combination therapy with lamivudine and tenofovir.
ISSN:	1398-2273 1399-3062
DOI:	10.1111/tid.12057