Safety and immunogenicity of a quadrivalent inactivated influenza vaccine compared to licensed trivalent inactivated influenza vaccines in adults

Safety and immunogenicity of a quadrivalent inactivated influenza vaccine compared to licensed trivalent inactivated influenza vaccines in adults

Highlights ► Two distinct lineages of influenza B virus co-circulate annually. ► The B lineage chosen for TIV is often not the B lineage that circulates. ► QIV contains two influenza B strains, one from each lineage. ► QIV was as safe and immunogenic as licensed TIV in adults. ► QIV should offer pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2013-01, Vol.31 (5), p.770-776
Hauptverfasser: Greenberg, David P, Robertson, Corwin A, Noss, Michael J, Blatter, Mark M, Biedenbender, Rex, Decker, Michael D
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Adults
Age
Aged
Aged, 80 and over
Allergy and Immunology
antibodies
Antibodies, Viral - blood
Antigens
Applied microbiology
Biological and medical sciences
confidence interval
Drug-Related Side Effects and Adverse Reactions - epidemiology
Female
Fundamental and applied biological sciences. Psychology
hemagglutination inhibition test
Hemagglutination Inhibition Tests
Humans
immune response
Immunization
Immunogenicity
Influenza
Influenza vaccine
Influenza Vaccines - administration & dosage
Influenza Vaccines - adverse effects
Influenza Vaccines - immunology
injection site
Licenses
Male
Microbiology
Middle Aged
Quadrivalent
Safety
Seasons
seroconversion
Serum - immunology
United States
vaccination
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Vaccines, Inactivated - administration & dosage
Vaccines, Inactivated - adverse effects
Vaccines, Inactivated - immunology
Young Adult
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highlights ► Two distinct lineages of influenza B virus co-circulate annually. ► The B lineage chosen for TIV is often not the B lineage that circulates. ► QIV contains two influenza B strains, one from each lineage. ► QIV was as safe and immunogenic as licensed TIV in adults. ► QIV should offer protection against both B lineages simultaneously.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.11.074