Apolipoprotein E, brain injury and neurodevelopmental outcome of children

Apolipoprotein E plays an important role in neurodegenerative processes in adulthood, whereas its neurodevelopmental role is uncertain. We aimed to study the effect of apolipoprotein E on neurodevelopment in a cohort liable to neurodevelopmental changes. The cohort consisted of very preterm (

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2013-04, Vol.12 (3), p.348-352
Hauptverfasser:	Korja, M., Ylijoki, M., Lapinleimu, H., Pohjola, P., Matomäki, J., Kuśmierek, H., Mahlman, M., Rikalainen, H., Parkkola, R., Kaukola, T., Lehtonen, L., Hallman, M., Haataja, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age APOE Apolipoprotein E Apolipoproteins Apolipoproteins E - genetics Babies Biological and medical sciences Birth weight Brain Injuries - diagnostic imaging Brain Injuries - genetics brain injury BSID‐II, FSIQ Child clinical studies Child Development Diseases of mother, fetus and pregnancy Female Genotype Gynecology. Andrology. Obstetrics Humans Infant, Extremely Premature Infant, Newborn Infant, Very Low Birth Weight Longitudinal Studies Magnetic Resonance Imaging Male Medical sciences neurodevelopment Organic mental disorders. Neuropsychology Pregnancy. Fetus. Placenta preterm Psychology. Psychoanalysis. Psychiatry Psychomotor Disorders - diagnostic imaging Psychomotor Disorders - genetics Psychopathology. Psychiatry Ultrasonic imaging Ultrasonography very low birth weight
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Zusammenfassung:	Apolipoprotein E plays an important role in neurodegenerative processes in adulthood, whereas its neurodevelopmental role is uncertain. We aimed to study the effect of apolipoprotein E on neurodevelopment in a cohort liable to neurodevelopmental changes. The cohort consisted of very preterm (
ISSN:	1601-1848 1601-183X
DOI:	10.1111/gbb.12024