The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system?
Highlights ► Complement activation is associated with placental malaria (PM) and fetal growth restriction. ► Complement plays a role in both neurodevelopment and neurological disease. ► PM may disrupt fetal neurodevelopment via excessive complement activation. ► PM may cause neurocognitive impairmen...
Gespeichert in:
| Veröffentlicht in: | Trends in parasitology 2013-05, Vol.29 (5), p.213-219 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 219 |
|---|---|
| container_issue | 5 |
| container_start_page | 213 |
| container_title | Trends in parasitology |
| container_volume | 29 |
| creator | McDonald, Chloe R Elphinstone, Robyn E Kain, Kevin C |
| description | Highlights ► Complement activation is associated with placental malaria (PM) and fetal growth restriction. ► Complement plays a role in both neurodevelopment and neurological disease. ► PM may disrupt fetal neurodevelopment via excessive complement activation. ► PM may cause neurocognitive impairment of infants exposed to malaria in utero. |
| doi_str_mv | 10.1016/j.pt.2013.03.005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1347465733</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1471492213000482</els_id><sourcerecordid>1347465733</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-eeaada7831ff3be580502ffd9e92a23b7146c492372e7d3f1afe49794ab6a9af3</originalsourceid><addsrcrecordid>eNp9kc2LFDEQxRtR3HX17kly9DJjJenuTO9BkcUvWPDgeg416QpmTCdtkl6c_960M3rwIBRUQX7vkXrVNM85bDnw_tVhO5etAC63UAu6B80lbxXfdADq4XluByEumic5HwB4p9TwuLkQsuuFUuqycXffiLlpRlNYtGz2aCgU9GxCj8khi4EFWlIc6Z58nKf6uoL0c46ZRuaCxVDyNUOWoidmY2KlWpo4zZ5-0_mYC01vnjaPLPpMz879qvn6_t3dzcfN7ecPn27e3m5M_W3ZECGOqHaSWyv31O2gA2HtONAgUMi94m1v6k5SCVKjtBwttYMaWtz3OKCVV83Lk--c4o-FctGTy4a8x0BxyZrLVrV9p6SsKJxQk2LOiayek5swHTUHvQasD3oueg1YQy3oquTF2X3ZTzT-FfxJtALXJ4DqjveOks7GUTA0ukSm6DG6_7m__kdsvAvOoP9OR8qHuKRQs9NcZ6FBf1kPvN6XSwBod0L-Ap40oRU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1347465733</pqid></control><display><type>article</type><title>The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system?</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>McDonald, Chloe R ; Elphinstone, Robyn E ; Kain, Kevin C</creator><creatorcontrib>McDonald, Chloe R ; Elphinstone, Robyn E ; Kain, Kevin C</creatorcontrib><description>Highlights ► Complement activation is associated with placental malaria (PM) and fetal growth restriction. ► Complement plays a role in both neurodevelopment and neurological disease. ► PM may disrupt fetal neurodevelopment via excessive complement activation. ► PM may cause neurocognitive impairment of infants exposed to malaria in utero.</description><identifier>ISSN: 1471-4922</identifier><identifier>EISSN: 1471-5007</identifier><identifier>DOI: 10.1016/j.pt.2013.03.005</identifier><identifier>PMID: 23562777</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Brain - embryology ; Brain - growth & development ; central nervous system development ; cognitive development ; Complement Activation ; complement cascade ; Complement System Proteins - immunology ; Female ; Gastroenterology and Hepatology ; Humans ; in utero environment ; Infant ; Infectious Disease ; malaria ; Malaria - complications ; Malaria - parasitology ; Malaria - physiopathology ; maternal infection ; Neurodegenerative Diseases - etiology ; Neurodegenerative Diseases - parasitology ; placenta ; Placenta - parasitology ; Plasmodium - physiology ; Pregnancy ; Pregnancy Complications, Parasitic - parasitology ; Pregnancy Complications, Parasitic - physiopathology</subject><ispartof>Trends in parasitology, 2013-05, Vol.29 (5), p.213-219</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-eeaada7831ff3be580502ffd9e92a23b7146c492372e7d3f1afe49794ab6a9af3</citedby><cites>FETCH-LOGICAL-c471t-eeaada7831ff3be580502ffd9e92a23b7146c492372e7d3f1afe49794ab6a9af3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.pt.2013.03.005$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23562777$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McDonald, Chloe R</creatorcontrib><creatorcontrib>Elphinstone, Robyn E</creatorcontrib><creatorcontrib>Kain, Kevin C</creatorcontrib><title>The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system?</title><title>Trends in parasitology</title><addtitle>Trends Parasitol</addtitle><description>Highlights ► Complement activation is associated with placental malaria (PM) and fetal growth restriction. ► Complement plays a role in both neurodevelopment and neurological disease. ► PM may disrupt fetal neurodevelopment via excessive complement activation. ► PM may cause neurocognitive impairment of infants exposed to malaria in utero.</description><subject>Animals</subject><subject>Brain - embryology</subject><subject>Brain - growth & development</subject><subject>central nervous system development</subject><subject>cognitive development</subject><subject>Complement Activation</subject><subject>complement cascade</subject><subject>Complement System Proteins - immunology</subject><subject>Female</subject><subject>Gastroenterology and Hepatology</subject><subject>Humans</subject><subject>in utero environment</subject><subject>Infant</subject><subject>Infectious Disease</subject><subject>malaria</subject><subject>Malaria - complications</subject><subject>Malaria - parasitology</subject><subject>Malaria - physiopathology</subject><subject>maternal infection</subject><subject>Neurodegenerative Diseases - etiology</subject><subject>Neurodegenerative Diseases - parasitology</subject><subject>placenta</subject><subject>Placenta - parasitology</subject><subject>Plasmodium - physiology</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Parasitic - parasitology</subject><subject>Pregnancy Complications, Parasitic - physiopathology</subject><issn>1471-4922</issn><issn>1471-5007</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc2LFDEQxRtR3HX17kly9DJjJenuTO9BkcUvWPDgeg416QpmTCdtkl6c_960M3rwIBRUQX7vkXrVNM85bDnw_tVhO5etAC63UAu6B80lbxXfdADq4XluByEumic5HwB4p9TwuLkQsuuFUuqycXffiLlpRlNYtGz2aCgU9GxCj8khi4EFWlIc6Z58nKf6uoL0c46ZRuaCxVDyNUOWoidmY2KlWpo4zZ5-0_mYC01vnjaPLPpMz879qvn6_t3dzcfN7ecPn27e3m5M_W3ZECGOqHaSWyv31O2gA2HtONAgUMi94m1v6k5SCVKjtBwttYMaWtz3OKCVV83Lk--c4o-FctGTy4a8x0BxyZrLVrV9p6SsKJxQk2LOiayek5swHTUHvQasD3oueg1YQy3oquTF2X3ZTzT-FfxJtALXJ4DqjveOks7GUTA0ukSm6DG6_7m__kdsvAvOoP9OR8qHuKRQs9NcZ6FBf1kPvN6XSwBod0L-Ap40oRU</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>McDonald, Chloe R</creator><creator>Elphinstone, Robyn E</creator><creator>Kain, Kevin C</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130501</creationdate><title>The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system?</title><author>McDonald, Chloe R ; Elphinstone, Robyn E ; Kain, Kevin C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-eeaada7831ff3be580502ffd9e92a23b7146c492372e7d3f1afe49794ab6a9af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Animals</topic><topic>Brain - embryology</topic><topic>Brain - growth & development</topic><topic>central nervous system development</topic><topic>cognitive development</topic><topic>Complement Activation</topic><topic>complement cascade</topic><topic>Complement System Proteins - immunology</topic><topic>Female</topic><topic>Gastroenterology and Hepatology</topic><topic>Humans</topic><topic>in utero environment</topic><topic>Infant</topic><topic>Infectious Disease</topic><topic>malaria</topic><topic>Malaria - complications</topic><topic>Malaria - parasitology</topic><topic>Malaria - physiopathology</topic><topic>maternal infection</topic><topic>Neurodegenerative Diseases - etiology</topic><topic>Neurodegenerative Diseases - parasitology</topic><topic>placenta</topic><topic>Placenta - parasitology</topic><topic>Plasmodium - physiology</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Parasitic - parasitology</topic><topic>Pregnancy Complications, Parasitic - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McDonald, Chloe R</creatorcontrib><creatorcontrib>Elphinstone, Robyn E</creatorcontrib><creatorcontrib>Kain, Kevin C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McDonald, Chloe R</au><au>Elphinstone, Robyn E</au><au>Kain, Kevin C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system?</atitle><jtitle>Trends in parasitology</jtitle><addtitle>Trends Parasitol</addtitle><date>2013-05-01</date><risdate>2013</risdate><volume>29</volume><issue>5</issue><spage>213</spage><epage>219</epage><pages>213-219</pages><issn>1471-4922</issn><eissn>1471-5007</eissn><abstract>Highlights ► Complement activation is associated with placental malaria (PM) and fetal growth restriction. ► Complement plays a role in both neurodevelopment and neurological disease. ► PM may disrupt fetal neurodevelopment via excessive complement activation. ► PM may cause neurocognitive impairment of infants exposed to malaria in utero.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>23562777</pmid><doi>10.1016/j.pt.2013.03.005</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1471-4922 |
| ispartof | Trends in parasitology, 2013-05, Vol.29 (5), p.213-219 |
| issn | 1471-4922 1471-5007 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1347465733 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Brain - embryology Brain - growth & development central nervous system development cognitive development Complement Activation complement cascade Complement System Proteins - immunology Female Gastroenterology and Hepatology Humans in utero environment Infant Infectious Disease malaria Malaria - complications Malaria - parasitology Malaria - physiopathology maternal infection Neurodegenerative Diseases - etiology Neurodegenerative Diseases - parasitology placenta Placenta - parasitology Plasmodium - physiology Pregnancy Pregnancy Complications, Parasitic - parasitology Pregnancy Complications, Parasitic - physiopathology |
| title | The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T10%3A52%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20impact%20of%20placental%20malaria%20on%20neurodevelopment%20of%20exposed%20infants:%20a%20role%20for%20the%20complement%20system?&rft.jtitle=Trends%20in%20parasitology&rft.au=McDonald,%20Chloe%20R&rft.date=2013-05-01&rft.volume=29&rft.issue=5&rft.spage=213&rft.epage=219&rft.pages=213-219&rft.issn=1471-4922&rft.eissn=1471-5007&rft_id=info:doi/10.1016/j.pt.2013.03.005&rft_dat=%3Cproquest_cross%3E1347465733%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1347465733&rft_id=info:pmid/23562777&rft_els_id=1_s2_0_S1471492213000482&rfr_iscdi=true |