Insulin-degrading enzyme deficiency accelerates cerebrovascular amyloidosis in an animal model
Highlights ► TGF-β1 can reduce insulin degrading enzyme expression in mouse brain endothelial cell resulting in cerebrovascular amyloidosis.
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| Veröffentlicht in: | Brain, behavior, and immunity behavior, and immunity, 2013-05, Vol.30, p.143-149 |
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| container_end_page | 149 |
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| container_start_page | 143 |
| container_title | Brain, behavior, and immunity |
| container_volume | 30 |
| creator | Lifshitz, Veronica Benromano, Tali Weiss, Ronen Blanga-Kanfi, Shani Frenkel, Dan |
| description | Highlights ► TGF-β1 can reduce insulin degrading enzyme expression in mouse brain endothelial cell resulting in cerebrovascular amyloidosis. |
| doi_str_mv | 10.1016/j.bbi.2012.12.003 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0889-1591 |
| ispartof | Brain, behavior, and immunity, 2013-05, Vol.30, p.143-149 |
| issn | 0889-1591 1090-2139 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Allergy and Immunology Alzheimer’s disease Amyloidosis - metabolism Amyloidosis - pathology Animals Astrocytes - metabolism Astrocytes - pathology Brain - metabolism Brain - pathology Cells, Cultured Cerebrovascular disease Cerebrovascular Disorders - metabolism Cerebrovascular Disorders - pathology Endothelial cells Endothelial Cells - metabolism Insulin-degrading enzyme Insulysin - deficiency Insulysin - metabolism Mice Mice, Transgenic Psychiatry Synaptophysin - metabolism TGF-β1 Transforming Growth Factor beta1 - genetics Transforming Growth Factor beta1 - metabolism |
| title | Insulin-degrading enzyme deficiency accelerates cerebrovascular amyloidosis in an animal model |
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