The Prevalence and Prognostic Role of Vitamin D Deficiency in Patients with Acute Coronary Syndrome: A Single Centre Study in South-West of Iran

Background The objectives of this study were estimating the prevalence of vitamin D deficiency in patients with acute coronary syndrome comparing with normal people and evaluating the relationship between vitamin D deficiency and short-term mortality in these patients. Methods We considered 106 patients with non-ST elevation myocardial infarction and high-risk unstable angina and 110 patients with ST elevation myocardial infarction as group A. The control group (group B) consisted of 120 individuals without any known cardiovascular diseases or systemic disease. We measured serum 25-hydroxyvitamin D in all cases and classified them according to their serum 25-hydroxyvitamin D levels. Sufficient vitamin D level was considered ≥30 ng/ml. We followed the patients for 30 days after index admission. Results The prevalence of hypovitaminosis D in group A was much higher than group B. In group A, 72% of patients had serum 25-hydroxyvitamin D level of 20 ng/ml or less. This percentage was only 27.4% in control group. We did not find any significant relationship between vitamin D deficiency and short-term mortality in patients with acute coronary syndrome. Conclusion Our data suggest that vitamin D deficiency was present in most of patients admitted with acute coronary syndrome in Ahvaz.