Benzophenones from an Endophytic Fungus, Graphiopsis chlorocephala, from Paeonia lactiflora Cultivated in the Presence of an NAD+‑Dependent HDAC Inhibitor

Graphiopsis chlorocephala was separated from the surface-sterilized healthy leaves of Paeonia lactiflora (Paeoniaceae) and cultivated with nicotinamide (an NAD+-dependent HDAC inhibitor). The culture conditions significantly enhanced secondary metabolite production in the fungus and led to the isola...

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Veröffentlicht in:Organic letters 2013-04, Vol.15 (8), p.2058-2061
Hauptverfasser: Asai, Teigo, Otsuki, Sae, Sakurai, Hiroaki, Yamashita, Kouwa, Ozeki, Tomoji, Oshima, Yoshiteru
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Sprache:eng
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