Addition of highly purified HMG after corifollitropin alfa in antagonist-treated poor ovarian responders: a pilot study

Addition of highly purified HMG after corifollitropin alfa in antagonist-treated poor ovarian responders: a pilot study

STUDY QUESTION Will sequential administration of highly purified (hp)-HMG after corifollitropin alfa in a GnRH antagonist protocol benefit women with poor ovarian response according to the Bologna criteria? SUMMARY ANSWER Corifollitropin alfa followed by hp-HMG in a GnRH antagonist protocol results...

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Veröffentlicht in:Human reproduction (Oxford) 2013-05, Vol.28 (5), p.1254-1260
Hauptverfasser: Polyzos, N.P., De Vos, M., Corona, R., Vloeberghs, V., Ortega-Hrepich, C., Stoop, D., Tournaye, H.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Female
Fertilization in Vitro - methods
Follicle Stimulating Hormone - therapeutic use
Follicle Stimulating Hormone, Human - therapeutic use
Gonadotropin-Releasing Hormone - antagonists & inhibitors
Humans
Luteinizing Hormone - therapeutic use
Menotropins - therapeutic use
Ovary - metabolism
Pilot Projects
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Recombinant Proteins - therapeutic use
Reproductive Techniques, Assisted - standards
Retrospective Studies
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Zusammenfassung:STUDY QUESTION Will sequential administration of highly purified (hp)-HMG after corifollitropin alfa in a GnRH antagonist protocol benefit women with poor ovarian response according to the Bologna criteria? SUMMARY ANSWER Corifollitropin alfa followed by hp-HMG in a GnRH antagonist protocol results in very promising pregnancy rates, albeit only in young (
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/det045