Benefits of replacing inorganic phosphorus by organic phosphorus in parenteral nutrition solutions administered to neonatal intensive care unit of a university hospital in Montes Claros - MG

The introduction of the parenteral nutrition was undoubtedly one of the factors that contributed to reduce mortality in neonatal intensive care unit in recent years. Given the low volumes used in neonatology, the issue that most challenges the current practice of pharmaceutical preparation of the solution is related to its physical and chemical stability with supplying adequate amounts of calcium and phosphorus. The higher the concentration of these ions, the greater the likelihood of precipitation of calcium salts, a serious problem in parenteral nutrition solutions. This study aimed to ascertain whether there are advantages that favor the substitution of inorganic phosphorus by organic phosphorus in parenteral nutrition solutions in neonatal intensive care unit consumed, since the hospitals that use inorganic source divide the parenteral solution in two bags, which would not be necessary with the use of organic phosphate.