Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response

This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication and the induction of immune response to the virus, including a new role for thymic stromal lymphopoietin in RSV immunopathology.

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Bibliographische Detailangaben
Veröffentlicht in:	Microbes and infection 2013-03, Vol.15 (3), p.230-242
Hauptverfasser:	Lay, Margarita K., González, Pablo A., León, Miguel A., Céspedes, Pablo F., Bueno, Susan M., Riedel, Claudia A., Kalergis, Alexis M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway epithelial cells Animals Cytokines - immunology Entry Epithelial Cells - immunology Epithelial Cells - pathology Epithelial Cells - virology Host-Pathogen Interactions - immunology Humans Immune response Replication cycle Respiratory Mucosa - immunology Respiratory Mucosa - pathology Respiratory Mucosa - virology Respiratory syncytial virus Respiratory Syncytial Virus Infections - immunology Respiratory Syncytial Virus Infections - pathology Respiratory Syncytial Virus Infections - virology Respiratory Syncytial Viruses - physiology RSV Thymic stromal lymphopoietin Virus Internalization Virus Replication
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Beschreibung
Zusammenfassung:	This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication and the induction of immune response to the virus, including a new role for thymic stromal lymphopoietin in RSV immunopathology.
ISSN:	1286-4579 1769-714X
DOI:	10.1016/j.micinf.2012.11.012