Evaluation of ADC measurements among solid pancreatic masses by respiratory-triggered diffusion-weighted MR imaging with inversion-recovery fat-suppression technique at 3.0T

The objective of this paper was to investigate the value of apparent diffusion coefficients (ADCs) for differential diagnosis among solid pancreatic masses using respiratory triggered diffusion-weighted MR imaging with inversion-recovery fat-suppression technique (RT-IR-DWI) at 3.0T. 20 normal volunteers and 72 patients (Pancreatic ductal adenocarcinoma [PDCA, n=30], mass-forming pancreatitis [MFP, n=15], solid pseudopapillary neoplasm [SPN, n=12], and pancreatic neuroendocrine tumor[PNET, n=15]) underwent RT-IR-DWI (b values: 0 and 600s/mm2) at 3.0T. Results were correlated with histopathologic data and follow-up imaging. ADC values among different types of pancreatic tissue were statistically analyzed and compared. Statistical difference was noticed in ADC values among normal pancreas, MFP, PDCA, SPN and PNET by ANOVA (p