Three-dimensional multiphoton/optical coherence tomography for diagnostic applications in dermatology

A preliminary clinical trial using state‐of‐the‐art multiphoton tomography (MPT) and optical coherence tomography (OCT) for three‐dimensional (3D) multimodal in vivo imaging of normal skin, nevi, scars and pathologic skin lesions has been conducted. MPT enabled visualization of sub‐cellular details...

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Veröffentlicht in:	Journal of biophotonics 2013-04, Vol.6 (4), p.352-362
Hauptverfasser:	Alex, Aneesh, Weingast, Jessika, Weinigel, Martin, Kellner-Höfer, Marcel, Nemecek, Romina, Binder, Michael, Pehamberger, Hubert, König, Karsten, Drexler, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Basal Cell - diagnosis Carcinoma, Basal Cell - pathology Cicatrix - diagnosis Cicatrix - pathology Dermatitis, Seborrheic - diagnosis Dermatitis, Seborrheic - pathology Dermatology Humans Imaging, Three-Dimensional - methods in vivo imaging multimodal imaging Multiphoton tomography Nevus - diagnosis Nevus - pathology non-invasive optical coherence tomography Photons Skin - cytology Skin - pathology Skin Diseases - diagnosis Skin Diseases - pathology Skin Neoplasms - diagnosis Skin Neoplasms - pathology three dimensional Tomography Tomography, Optical Coherence - methods
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Zusammenfassung:	A preliminary clinical trial using state‐of‐the‐art multiphoton tomography (MPT) and optical coherence tomography (OCT) for three‐dimensional (3D) multimodal in vivo imaging of normal skin, nevi, scars and pathologic skin lesions has been conducted. MPT enabled visualization of sub‐cellular details with axial and transverse resolutions of
ISSN:	1864-063X 1864-0648
DOI:	10.1002/jbio.201200085