Engineering strategies aimed at control of acidification rate of lactic acid bacteria

Graphical abstract Highlights ► Flux control does not reside in individual glycolytic enzymes in L. lactis . ► ATP demand does not control the glycolytic flux in L. lactis . ► Lactic acid bacteria are excellent candidates for the cell factories of the future.

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Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in biotechnology 2013-04, Vol.24 (2), p.124-129
Hauptverfasser:	Martinussen, Jan, Solem, Christian, Holm, Anders Koefoed, Jensen, Peter Ruhdal
Format:	Artikel
Sprache:	eng
Schlagworte:	acetic acid acidification Adenosine Triphosphate - metabolism Bioreactors Biotechnology engineering Fermentation fuels Glucose - metabolism Glycolysis Hydrogen-Ion Concentration Internal Medicine lactic acid Lactic Acid - metabolism lactic acid bacteria Lactobacillus - metabolism pyruvic acid Pyruvic Acid - metabolism sugars
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Beschreibung
Zusammenfassung:	Graphical abstract Highlights ► Flux control does not reside in individual glycolytic enzymes in L. lactis . ► ATP demand does not control the glycolytic flux in L. lactis . ► Lactic acid bacteria are excellent candidates for the cell factories of the future.
ISSN:	0958-1669 1879-0429
DOI:	10.1016/j.copbio.2012.11.009