Engineering plant metabolism into microbes: from systems biology to synthetic biology

Engineering plant metabolism into microbes: from systems biology to synthetic biology

Graphical abstract Highlights ► Microbial production of pharmaceutical and fuel molecules. ► Systems biology tools advanced our understanding about synthetic pathway design. ► Synthetic biology led us to cell factories tailor-made for chemical production. ► Combinatorial gene assembly for synthetic...

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Veröffentlicht in:Current opinion in biotechnology 2013-04, Vol.24 (2), p.291-299
Hauptverfasser: Xu, Peng, Bhan, Namita, Koffas, Mattheos AG
Format: Artikel
Sprache:eng
Schlagworte:
biochemical pathways
biology
Biosynthetic Pathways - genetics
Biotechnology - methods
fossil fuels
fuels
genes
Internal Medicine
Metabolic Engineering
Metabolic Networks and Pathways - genetics
metabolism
Microbiology
microorganisms
Plants - genetics
Plants - metabolism
prediction
Synthetic Biology
Systems Biology
yields
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Beschreibung
Zusammenfassung:Graphical abstract Highlights ► Microbial production of pharmaceutical and fuel molecules. ► Systems biology tools advanced our understanding about synthetic pathway design. ► Synthetic biology led us to cell factories tailor-made for chemical production. ► Combinatorial gene assembly for synthetic pathway diversification. ► Engineering static, dynamic and spatial control for better production phenotype.
ISSN:0958-1669
1879-0429
DOI:10.1016/j.copbio.2012.08.010