MicroRNA functions in insects
MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and viruses. Their role as master regulators of gene expression in various biological processes has only been fully appreciated over the last decade. Accumulating evidence suggests that alterations in the expression of...
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Veröffentlicht in: | Insect biochemistry and molecular biology 2013-04, Vol.43 (4), p.388-397 |
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description | MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and viruses. Their role as master regulators of gene expression in various biological processes has only been fully appreciated over the last decade. Accumulating evidence suggests that alterations in the expression of miRNAs may lead to disorders, including developmental defects, diseases and cancer. Here, I review what is currently known about miRNA functions in insects to provide an insight into their diverse roles in insect biology.
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► MicroRNAs are ∼22 nucleotide non-coding RNAs produced in all eukaryotes. ► MicroRNAs are key regulators of gene expression at the post-transcriptional level. ► In insects, microRNAs are involved in various functions, including development, immunity and host–pathogen interactions. |
doi_str_mv | 10.1016/j.ibmb.2012.10.005 |
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► MicroRNAs are ∼22 nucleotide non-coding RNAs produced in all eukaryotes. ► MicroRNAs are key regulators of gene expression at the post-transcriptional level. ► In insects, microRNAs are involved in various functions, including development, immunity and host–pathogen interactions.</description><identifier>ISSN: 0965-1748</identifier><identifier>EISSN: 1879-0240</identifier><identifier>DOI: 10.1016/j.ibmb.2012.10.005</identifier><identifier>PMID: 23103375</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Development ; eukaryotic cells ; gene expression ; Gene Expression Regulation, Developmental ; Gene regulation ; Host-Pathogen Interactions ; Host–pathogen interaction ; insect biology ; Insecta - genetics ; Insecta - growth & development ; Insecta - physiology ; insects ; microRNA ; MicroRNAs - genetics ; MicroRNAs - metabolism ; non-coding RNA ; viruses</subject><ispartof>Insect biochemistry and molecular biology, 2013-04, Vol.43 (4), p.388-397</ispartof><rights>2012 Elsevier Ltd</rights><rights>Copyright © 2012 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-a5c94eb5d9c5fdab33f1bee60fe5a4515f15fb9ea506f74d19b3ab7bcd2bf74f3</citedby><cites>FETCH-LOGICAL-c446t-a5c94eb5d9c5fdab33f1bee60fe5a4515f15fb9ea506f74d19b3ab7bcd2bf74f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ibmb.2012.10.005$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23103375$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asgari, Sassan</creatorcontrib><title>MicroRNA functions in insects</title><title>Insect biochemistry and molecular biology</title><addtitle>Insect Biochem Mol Biol</addtitle><description>MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and viruses. Their role as master regulators of gene expression in various biological processes has only been fully appreciated over the last decade. Accumulating evidence suggests that alterations in the expression of miRNAs may lead to disorders, including developmental defects, diseases and cancer. Here, I review what is currently known about miRNA functions in insects to provide an insight into their diverse roles in insect biology.
[Display omitted]
► MicroRNAs are ∼22 nucleotide non-coding RNAs produced in all eukaryotes. ► MicroRNAs are key regulators of gene expression at the post-transcriptional level. ► In insects, microRNAs are involved in various functions, including development, immunity and host–pathogen interactions.</description><subject>Animals</subject><subject>Development</subject><subject>eukaryotic cells</subject><subject>gene expression</subject><subject>Gene Expression Regulation, Developmental</subject><subject>Gene regulation</subject><subject>Host-Pathogen Interactions</subject><subject>Host–pathogen interaction</subject><subject>insect biology</subject><subject>Insecta - genetics</subject><subject>Insecta - growth & development</subject><subject>Insecta - physiology</subject><subject>insects</subject><subject>microRNA</subject><subject>MicroRNAs - genetics</subject><subject>MicroRNAs - metabolism</subject><subject>non-coding RNA</subject><subject>viruses</subject><issn>0965-1748</issn><issn>1879-0240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1LwzAUhoMobk7_gKDu0pvOk6-2AW_G8AumgrrrkKSJZKztbFrBf29Kp5ciHAg5POc9yYPQKYYZBpxerWdel3pGAJPYmAHwPTTGeSYSIAz20RhEyhOcsXyEjkJYAwBjPDtEI0IxUJrxMTp79KapX57mU9dVpvV1Faa-ihWsacMxOnBqE-zJ7pyg1e3N2-I-WT7fPSzmy8QwlraJ4kYwq3khDHeF0pQ6rK1NwVmuGMfcxdLCKg6py1iBhaZKZ9oURMe7oxN0OeRum_qjs6GVpQ_GbjaqsnUXJKaE5kAEF_9AcZZzTiCLKBnQ-MMQGuvktvGlar4kBtkblGvZG5S9wb4XDcah811-p0tb_I78KIvAxQA4VUv13vggV68xgUe9OeSi33s9EDYq-_S2kcF4Wxlb-CZalUXt_3rBN1yciYc</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>Asgari, Sassan</creator><general>Elsevier Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SS</scope></search><sort><creationdate>20130401</creationdate><title>MicroRNA functions in insects</title><author>Asgari, Sassan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-a5c94eb5d9c5fdab33f1bee60fe5a4515f15fb9ea506f74d19b3ab7bcd2bf74f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Animals</topic><topic>Development</topic><topic>eukaryotic cells</topic><topic>gene expression</topic><topic>Gene Expression Regulation, Developmental</topic><topic>Gene regulation</topic><topic>Host-Pathogen Interactions</topic><topic>Host–pathogen interaction</topic><topic>insect biology</topic><topic>Insecta - genetics</topic><topic>Insecta - growth & development</topic><topic>Insecta - physiology</topic><topic>insects</topic><topic>microRNA</topic><topic>MicroRNAs - genetics</topic><topic>MicroRNAs - metabolism</topic><topic>non-coding RNA</topic><topic>viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asgari, Sassan</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Entomology Abstracts (Full archive)</collection><jtitle>Insect biochemistry and molecular biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asgari, Sassan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MicroRNA functions in insects</atitle><jtitle>Insect biochemistry and molecular biology</jtitle><addtitle>Insect Biochem Mol Biol</addtitle><date>2013-04-01</date><risdate>2013</risdate><volume>43</volume><issue>4</issue><spage>388</spage><epage>397</epage><pages>388-397</pages><issn>0965-1748</issn><eissn>1879-0240</eissn><abstract>MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and viruses. Their role as master regulators of gene expression in various biological processes has only been fully appreciated over the last decade. Accumulating evidence suggests that alterations in the expression of miRNAs may lead to disorders, including developmental defects, diseases and cancer. Here, I review what is currently known about miRNA functions in insects to provide an insight into their diverse roles in insect biology.
[Display omitted]
► MicroRNAs are ∼22 nucleotide non-coding RNAs produced in all eukaryotes. ► MicroRNAs are key regulators of gene expression at the post-transcriptional level. ► In insects, microRNAs are involved in various functions, including development, immunity and host–pathogen interactions.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>23103375</pmid><doi>10.1016/j.ibmb.2012.10.005</doi><tpages>10</tpages></addata></record> |
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subjects | Animals Development eukaryotic cells gene expression Gene Expression Regulation, Developmental Gene regulation Host-Pathogen Interactions Host–pathogen interaction insect biology Insecta - genetics Insecta - growth & development Insecta - physiology insects microRNA MicroRNAs - genetics MicroRNAs - metabolism non-coding RNA viruses |
title | MicroRNA functions in insects |
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