MicroRNA functions in insects

MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and viruses. Their role as master regulators of gene expression in various biological processes has only been fully appreciated over the last decade. Accumulating evidence suggests that alterations in the expression of...

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Veröffentlicht in:Insect biochemistry and molecular biology 2013-04, Vol.43 (4), p.388-397
1. Verfasser: Asgari, Sassan
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description MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and viruses. Their role as master regulators of gene expression in various biological processes has only been fully appreciated over the last decade. Accumulating evidence suggests that alterations in the expression of miRNAs may lead to disorders, including developmental defects, diseases and cancer. Here, I review what is currently known about miRNA functions in insects to provide an insight into their diverse roles in insect biology. [Display omitted] ► MicroRNAs are ∼22 nucleotide non-coding RNAs produced in all eukaryotes. ► MicroRNAs are key regulators of gene expression at the post-transcriptional level. ► In insects, microRNAs are involved in various functions, including development, immunity and host–pathogen interactions.
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Animals
Development
eukaryotic cells
gene expression
Gene Expression Regulation, Developmental
Gene regulation
Host-Pathogen Interactions
Host–pathogen interaction
insect biology
Insecta - genetics
Insecta - growth & development
Insecta - physiology
insects
microRNA
MicroRNAs - genetics
MicroRNAs - metabolism
non-coding RNA
viruses
title MicroRNA functions in insects
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