Diuretic activity and acute oral toxicity of Palicourea coriacea (Cham.) K Schum

Effects of Palicourea coriacea ethanolic extract (20, 40, and 80mg/kg) on the cumulative urinary volume excretion (1–24h). In all treatments schedule, rats were orally treated with a single dose of the ethanolic extract or with the positive control, furosemide (F, 20mg/kg). The control group receive...

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Veröffentlicht in:	Journal of ethnopharmacology 2011-03, Vol.134 (2), p.501-503
Hauptverfasser:	Freitas, P.C.M., Pucci, L.L., Vieira, M.S., Lino, R.S., Oliveira, C.M.A., Cunha, L.C., Paula, J.R., Valadares, M.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute oral toxicity Administration, Oral Animals Biodiversity Biological and medical sciences Brazil Conservation Diuretic Diuretics Diuretics - pharmacology Diuretics - toxicity Dose-Response Relationship, Drug Excretion General pharmacology Kidney diseases Male Medical sciences Medicinal plants Medicine, Traditional Oral administration Palicourea Palicourea coriacea Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Plant Extracts - toxicity Potassium - urine Preservation Rats Rats, Wistar Rubiaceae Rubiaceae - toxicity Sodium - urine Toxicity Urination - drug effects
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Zusammenfassung:	Effects of Palicourea coriacea ethanolic extract (20, 40, and 80mg/kg) on the cumulative urinary volume excretion (1–24h). In all treatments schedule, rats were orally treated with a single dose of the ethanolic extract or with the positive control, furosemide (F, 20mg/kg). The control group received saline only. Data are expressed as means±SEM; n=6 rats per group; *p
ISSN:	0378-8741 1872-7573
DOI:	10.1016/j.jep.2010.12.002