Estimated contribution of hemoglobin and myoglobin to near infrared spectroscopy

Highlights ► Skeletal muscle hemoglobin and myoglobin contributions to near infrared spectroscopy at rest were estimated from values in the literature. ► Contrary to popular opinion, myoglobin was estimated to contribute up to 40–70% of the NIRS signals. ► Changes in total (hemoglobin + myoglobin) i...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2013-04, Vol.186 (2), p.180-187
Hauptverfasser:	Davis, Michelle L, Barstow, Thomas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Exercise Exercise - physiology Hemoglobin Hemoglobins - analysis Humans Medical Education Muscle Muscle, Skeletal - blood supply Muscle, Skeletal - chemistry Myoglobin Myoglobin - analysis Near infrared spectroscopy Pulmonary/Respiratory Spectroscopy, Near-Infrared
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Beschreibung
Zusammenfassung:	Highlights ► Skeletal muscle hemoglobin and myoglobin contributions to near infrared spectroscopy at rest were estimated from values in the literature. ► Contrary to popular opinion, myoglobin was estimated to contribute up to 40–70% of the NIRS signals. ► Changes in total (hemoglobin + myoglobin) in humans during exercise (assumed to reflect changes in hemoglobin) can be explained by our modeling and suggest that myoglobin contributes significantly to the NIRS signals.
ISSN:	1569-9048 1878-1519
DOI:	10.1016/j.resp.2013.01.012