CO2 homeostasis is maintained in conscious humans by regulation of tidal volume, but not of respiratory rhythm

Graphical abstract Highlights ► We measured end-tidal CO2 fraction during two types of volitional breathing. ► Either (1) respiratory frequency or (2) tidal volume was volitionally constrained. ► CO2 level was maintained when respiratory frequency was volitionally constrained. ► CO2 level was decrea...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2013-04, Vol.186 (2), p.155-163
Hauptverfasser:	Ohashi, Suguru, Izumizaki, Masahiko, Atsumi, Takashi, Homma, Ikuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Behavior Carbon Dioxide - metabolism Conscious humans Consciousness Homeostasis - physiology Humans Hypocapnia Male Medical Education Middle Aged Pulmonary Gas Exchange - physiology Pulmonary/Respiratory Respiration Respiratory frequency Respiratory Mechanics - physiology Tidal volume Tidal Volume - physiology Young Adult
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Zusammenfassung:	Graphical abstract Highlights ► We measured end-tidal CO2 fraction during two types of volitional breathing. ► Either (1) respiratory frequency or (2) tidal volume was volitionally constrained. ► CO2 level was maintained when respiratory frequency was volitionally constrained. ► CO2 level was decreased when tidal volume was volitionally constrained. ► CO2 homeostasis is maintained in conscious humans by regulation of tidal volume.
ISSN:	1569-9048 1878-1519
DOI:	10.1016/j.resp.2013.01.008