Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay

Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay

The dansyl fluorophore ligated to gold nanoparticles via imidazole and amine groups affords conjugates capable of detecting micromolar concentrations of the chemical warfare agent sulfur mustard by a fluorescence switching 'ON' displacement assay.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (23), p.2293-2295
Hauptverfasser: Knighton, Richard C, Sambrook, Mark R, Vincent, Jack C, Smith, Simon A, Serpell, Christopher J, Cookson, James, Vickers, Matthew S, Beer, Paul D
Format: Artikel
Sprache:eng
Schlagworte:
Amines - chemistry
Assaying
Chemical Warfare Agents - analysis
Conjugates
Displacement
Fluorescent Dyes - chemistry
Gold
Gold - chemistry
Imidazoles - chemistry
Metal Nanoparticles - chemistry
Mustard
Mustard Gas - analysis
Nanoparticles
Phosphatidylcholines - chemistry
Spectrophotometry, Ultraviolet
Sulfur
Switching
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Beschreibung
Zusammenfassung:The dansyl fluorophore ligated to gold nanoparticles via imidazole and amine groups affords conjugates capable of detecting micromolar concentrations of the chemical warfare agent sulfur mustard by a fluorescence switching 'ON' displacement assay.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc39105a