ROS Links Glucose Metabolism to Breast Cancer Stem Cell and EMT Phenotype
Cancer stem cells display an epithelial-mesenchymal transition phenotype and are resistant to current therapies. In this issue of Cancer Cell, Dong and colleagues demonstrate that these phenotypes in basal-like breast cancer are promoted by a metabolic switch to glucose metabolism, resulting in decr...
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| Veröffentlicht in: | Cancer cell 2013-03, Vol.23 (3), p.265-267 |
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| container_end_page | 267 |
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| container_title | Cancer cell |
| container_volume | 23 |
| creator | Schieber, Michael S. Chandel, Navdeep S. |
| description | Cancer stem cells display an epithelial-mesenchymal transition phenotype and are resistant to current therapies. In this issue of Cancer Cell, Dong and colleagues demonstrate that these phenotypes in basal-like breast cancer are promoted by a metabolic switch to glucose metabolism, resulting in decreased reactive oxygen species levels. |
| doi_str_mv | 10.1016/j.ccr.2013.02.021 |
| format | Article |
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| ispartof | Cancer cell, 2013-03, Vol.23 (3), p.265-267 |
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| language | eng |
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| source | Cell Press Free Archives; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| title | ROS Links Glucose Metabolism to Breast Cancer Stem Cell and EMT Phenotype |
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