Activity of doripenem versus comparators in subjects with baseline bacteraemia in six pooled phase 3 clinical trials

An analysis of subjects with concurrent bacteraemia and either nosocomial pneumonia, complicated intra-abdominal infection or complicated urinary tract infection from six phase 3 clinical trials demonstrated similar cure rates and clearance of bacteraemia in patients treated with doripenem and compa...

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Veröffentlicht in:	International journal of antimicrobial agents 2013-04, Vol.41 (4), p.388-392
Hauptverfasser:	Rice, Dennis A.K, Kaniga, Koné, Lee, Michael, Redman, Rebecca
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use anti-infective agents Bacteraemia bacteremia Bacteremia - drug therapy Bacteremia - microbiology Carbapenem Carbapenems - therapeutic use clinical trials Complicated intra-abdominal infection Complicated urinary tract infection Cross Infection - drug therapy Cross Infection - microbiology Doripenem Female Humans Imipenem - therapeutic use Infectious Disease Intraabdominal Infections - drug therapy Intraabdominal Infections - microbiology Male Nosocomial pneumonia Ofloxacin - therapeutic use patients pneumonia Pneumonia - drug therapy Pneumonia - microbiology Thienamycins - therapeutic use Treatment Outcome urinary tract diseases Urinary Tract Infections - drug therapy Urinary Tract Infections - microbiology
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Zusammenfassung:	An analysis of subjects with concurrent bacteraemia and either nosocomial pneumonia, complicated intra-abdominal infection or complicated urinary tract infection from six phase 3 clinical trials demonstrated similar cure rates and clearance of bacteraemia in patients treated with doripenem and comparator agents.
ISSN:	0924-8579 1872-7913
DOI:	10.1016/j.ijantimicag.2012.12.016