Effects of Nonstarch Polysaccharides with Different Molecular Weights on the Development of Lewis Lung Carcinoma in Mice and Efficiency of Cytostatic Therapy

The effects of nonstarch polysaccharides with different molecular weights on the development of Lewis’ lung carcinoma and efficiency of cyclophosphamide therapy in mice were studied. Treatment with these substances with low molecular weights (400 kDa) inhibited the growth of Lewis’ lung carcinoma no...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2013-02, Vol.154 (4), p.492-496
Hauptverfasser:	Rybalkina, O. Yu, Razina, T. G., Lopatina, K. A., Amosova, E. N., Krylova, S. G., Efimova, L. A., Safonova, E. A., Zueva, E. P., Khotimchenko, M. Yu, Khotimchenko, Yu. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cancer Carcinoma Carcinoma, Lewis Lung - drug therapy Carcinoma, Lewis Lung - pathology Cell Biology Chemotherapy Cyclophosphamide Cyclophosphamide - therapeutic use Drug Synergism Female Internal Medicine Laboratory Medicine Lung cancer Mice Mice, Inbred C57BL Molecular Weight Monoclonal antibodies Oncology Pathology Polysaccharides Polysaccharides - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The effects of nonstarch polysaccharides with different molecular weights on the development of Lewis’ lung carcinoma and efficiency of cyclophosphamide therapy in mice were studied. Treatment with these substances with low molecular weights (400 kDa) inhibited the growth of Lewis’ lung carcinoma node. Antimetastatic effects of cyclophosphamide were stimulated by low and high molecular weight polysaccharides.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-013-1985-8