Enhanced separation of colloidal particles in an AsPFF device with a tilted sidewall and vertical focusing channels (t-AsPFF-v)

Here, we report an enhanced separation of colloidal particles using a novel type AsPFF (asymmetric pinched flow fractionation) device with two additional features (t-AsPFF-v). Particularly, by adding a tilted sidewall and vertical focusing channels to the conventional AsPFF device, a significant enhancement in the separation resolution (R(m,n)) has been achieved, which was estimated to be 10.4 for 6 and 10 μm PS particles and found to be 11.6 times better than that of a conventional AsPFF.