Rewriting the bacterial glycocalyx via Suzuki-Miyaura cross-coupling
Suzuki-Miyaura cross-coupling has been used to couple novel carbohydrate-based boronic acids, site-selectively, to the surface of E. coli at an unnatural amino acid. In this way, benign metal-catalyzed cellular switching allowed modulation of interactions with biomolecular partners via prokaryotic O...
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (27), p.2747-2749 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Suzuki-Miyaura cross-coupling has been used to couple novel carbohydrate-based boronic acids, site-selectively, to the surface of E. coli at an unnatural amino acid. In this way, benign metal-catalyzed cellular switching allowed modulation of interactions with biomolecular partners via prokaryotic O-glycosylation mimics. |
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ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c3cc38824g |