Dysfunctional and compensatory duality in mild cognitive impairment during a continuous recognition memory task

One of the current issues of debate in the study of mild cognitive impairment (MCI) is deviations of oscillatory brain responses from normal brain states and its dynamics. This work aims to characterize the differences of power in brain oscillations during the execution of a recognition memory task...

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Veröffentlicht in:International journal of psychophysiology 2013-01, Vol.87 (1), p.95-102
Hauptverfasser: Aurtenetxe, Sara, Castellanos, Nazareth P., Moratti, Stephan, Bajo, Ricardo, Gil, Pedro, Beitia, Garikoitz, del-Pozo, Francisco, Maestú, Fernando
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Sprache:eng
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Zusammenfassung:One of the current issues of debate in the study of mild cognitive impairment (MCI) is deviations of oscillatory brain responses from normal brain states and its dynamics. This work aims to characterize the differences of power in brain oscillations during the execution of a recognition memory task in MCI subjects in comparison with elderly controls. Magnetoencephalographic (MEG) signals were recorded during a continuous recognition memory task performance. Oscillatory brain activity during the recognition phase of the task was analyzed by wavelet transform in the source space by means of minimum norm algorithm. Both groups obtained a 77% hit ratio. In comparison with healthy controls, MCI subjects showed increased theta (p
ISSN:0167-8760
1872-7697
DOI:10.1016/j.ijpsycho.2012.11.008