Scratching the catalytic surface of mechanochemistry: a multi-component CuAAC reaction using a copper reaction vial

Herein we report the first copper vial catalysed CuAAC reaction. Under solvent-free mechanochemical conditions the reaction is complete in as little as 15 minutes and the triazole product isolated straight from the reaction vial with no further purification.

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Veröffentlicht in:	Green chemistry : an international journal and green chemistry resource : GC 2013-01, Vol.15 (3), p.617-619
Hauptverfasser:	COOK, Teresa L, WALKER, James A, MACK, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Chemistry Exact sciences and technology General and physical chemistry Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Organic chemistry Preparations and properties Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry
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Beschreibung
Zusammenfassung:	Herein we report the first copper vial catalysed CuAAC reaction. Under solvent-free mechanochemical conditions the reaction is complete in as little as 15 minutes and the triazole product isolated straight from the reaction vial with no further purification.
ISSN:	1463-9262 1463-9270
DOI:	10.1039/c3gc36720g