In vitro immunomodulating activity of β-heptylglycoside muramyldipeptide

In vitro immunomodulating activity of β-heptylglycoside muramyldipeptide

The effects of beta -heptylglycoside muramyldipeptide (glymuride) on antibody production and delayed type hypersensitivity reaction were studied in mice with weak and strong reactions to sheep erythrocytes. The drug exhibited high immunomodulating activity which depended on the initial genetically d...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1999-11, Vol.128 (5), p.1140-1141
Hauptverfasser: Kalyuzhin, O. V., Zakharova, N. S., Britsina, M. V., Zemlyakov, A. E., Kalyuzhin, V. V.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Drugs
Erythrocytes
Hypersensitivity (delayed)
Immunoreactivity
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Zusammenfassung:The effects of beta -heptylglycoside muramyldipeptide (glymuride) on antibody production and delayed type hypersensitivity reaction were studied in mice with weak and strong reactions to sheep erythrocytes. The drug exhibited high immunomodulating activity which depended on the initial genetically determined immunoreactivity of animals and drug dose.
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02433422