The validity of biochemical markers in metabolic bone disease in preterm infants: a systematic review

To establish the validity of biochemical markers of metabolic bone disease (MBD) in preterm infants. Conclusion:  There is insufficient evidence that any of the frequently used serum measurements are valid biochemical markers of MBD in preterm infants. Increased urinary calcium concentration may be...

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Veröffentlicht in:Acta Paediatrica 2012-06, Vol.101 (6), p.562-568
Hauptverfasser: Visser, Fenna, Sprij, Arwen J, Brus, Frank
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container_title Acta Paediatrica
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creator Visser, Fenna
Sprij, Arwen J
Brus, Frank
description To establish the validity of biochemical markers of metabolic bone disease (MBD) in preterm infants. Conclusion:  There is insufficient evidence that any of the frequently used serum measurements are valid biochemical markers of MBD in preterm infants. Increased urinary calcium concentration may be a valid biochemical marker, but more research is necessary to confirm this.
doi_str_mv 10.1111/j.1651-2227.2012.02626.x
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection
subjects Babies
Biochemical markers
Biological and medical sciences
Biomarkers - blood
Biomarkers - urine
Bone diseases
Bone Diseases, Metabolic - blood
Bone Diseases, Metabolic - urine
Calcium (urinary)
General aspects
Humans
Infant
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - urine
Infants
Medical sciences
Metabolic bone diseases
Neonatology
Premature birth
Premature infants
Reproducibility of Results
Reviews
Validity
title The validity of biochemical markers in metabolic bone disease in preterm infants: a systematic review
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