Single Walled Carbon Nanotubes/polypyrrole–GOx composite films to modify gold microelectrodes for glucose biosensors: Study of the extended linearity

A glucose biosensor was assembled using gold microelectrodes (diameter of 250μm) coated by Single-Walled Carbon Nanotubes (SWCNTs), via the Electrophoresis Deposition Process (EPD). This nanostructured platform was successfully used to deposit the poly(pyrrole)/glucose oxidase film (PPy/GOx). The most important result of this biosensors was the wide linear range of concentration, ranging from 4 to100mM (covering the hypo- and hyper-glycemia range, useful in diabetes). This extended linearity offered the possibility to measure glucose from 0.560 to 12.0mM, with a detection limit of 50μM (useful for hypo-glycemia disease). ► Nanotechnology and Nanomaterials for sensors and biosensors assembly. ► Nanomaterials characterization and biosensors performances. ► Nanomaterials and biological catalysts interfaces for a right comunication. ► Surface chemistry of nanomaterials should be controlled and certantly considered. ► Undesrtanding nano and meso-porosity.