Bevacizumab treatment for symptomatic radiation necrosis diagnosed by amino acid PET

Bevacizumab is effective in treating radiation necrosis; however, radiation necrosis was not definitively diagnosed in most previous reports. Here we used amino acid positron emission tomography to diagnose radiation necrosis for the application of bevacizumab in treating progressive radiation necro...

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Veröffentlicht in:	Japanese journal of clinical oncology 2013-03, Vol.43 (3), p.337-341
Hauptverfasser:	Furuse, Motomasa, Nonoguchi, Naosuke, Kawabata, Shinji, Yoritsune, Erina, Takahashi, Masatsugu, Inomata, Taisuke, Kuroiwa, Toshihiko, Miyatake, Shin-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amino Acids Antibodies, Monoclonal, Humanized - therapeutic use Bevacizumab Brain Neoplasms - radiotherapy Female Humans Male Middle Aged Necrosis - diagnosis Necrosis - drug therapy Necrosis - etiology Radiation Injuries - diagnosis Radiation Injuries - diagnostic imaging Radiation Injuries - drug therapy Radiotherapy - adverse effects Tomography, Emission-Computed - methods
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Zusammenfassung:	Bevacizumab is effective in treating radiation necrosis; however, radiation necrosis was not definitively diagnosed in most previous reports. Here we used amino acid positron emission tomography to diagnose radiation necrosis for the application of bevacizumab in treating progressive radiation necrosis. Lesion/normal tissue ratios of
ISSN:	0368-2811 1465-3621
DOI:	10.1093/jjco/hys231