Sweet Bing Cherries Lower Circulating Concentrations of Markers for Chronic Inflammatory Diseases in Healthy Humans

A limited number of studies have demonstrated that some modulators of inflammation can be altered by the consumption of sweet cherries. We have taken a proteomics approach to determine the effects of dietary cherries on targeted gene expression. The purpose was then to determine changes caused by ch...

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Veröffentlicht in:	The Journal of nutrition 2013-03, Vol.143 (3), p.340-344
Hauptverfasser:	Kelley, Darshan S., Adkins, Yuriko, Reddy, Aurosis, Woodhouse, Leslie R., Mackey, Bruce E., Erickson, Kent L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers - blood C-Reactive Protein - metabolism Chronic Disease Diet Dietary Supplements Endothelin-1 - blood Epidermal Growth Factor - blood Feeding. Feeding behavior Female Ferritins - blood Fruit Fundamental and applied biological sciences. Psychology Humans Inflammation - blood Inflammation - prevention & control Inflammation Mediators - blood Interleukin-18 - blood Male Middle Aged Phytotherapy Plant Preparations - pharmacology Plant Preparations - therapeutic use Plasminogen Activator Inhibitor 1 - blood Proteomics Prunus Receptors, Interleukin-1 - blood Reference Values Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Beschreibung
Zusammenfassung:	A limited number of studies have demonstrated that some modulators of inflammation can be altered by the consumption of sweet cherries. We have taken a proteomics approach to determine the effects of dietary cherries on targeted gene expression. The purpose was then to determine changes caused by cherry consumption in the plasma concentrations of multiple biomarkers for several chronic inflammatory diseases in healthy humans with modestly elevated C-reactive protein (CRP; range, 1–14 mg/L; mean, 3.5 mg/L; normal,
ISSN:	0022-3166 1541-6100
DOI:	10.3945/jn.112.171371