Dose and effect biomarkers in the diagnosis of asbestos-related diseases and health surveillance of exposed workers

Dose and effect biomarkers in the diagnosis of asbestos-related diseases and health surveillance of exposed workers

The aim of the study was to assess the reliability of the indicators of dose and effect in the health monitoring of asbestos exposed workers. In 49 cases out of 158 studied workers (31%) asbestos-related diseases were diagnosed following ATS criteria (2004). Using nonparametric statistical methods (...

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Veröffentlicht in:Giornale italiano di medicina del lavoro ed ergonomia 2012-07, Vol.34 (3 Suppl), p.577-580
Hauptverfasser: Montomoli, L, Romeo, R, Sisinni, A G, Serio, A C, Paolucci, V, Scancarello, G, Barabesi, L, Orsi, D, Sartorelli, P
Format: Artikel
Sprache:ita
Schlagworte:
Adult
Aged
Aged, 80 and over
Asbestosis - diagnosis
Biomarkers - analysis
Female
Humans
Male
Middle Aged
Occupational Diseases - diagnosis
Occupational Exposure - adverse effects
Population Surveillance
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Zusammenfassung:The aim of the study was to assess the reliability of the indicators of dose and effect in the health monitoring of asbestos exposed workers. In 49 cases out of 158 studied workers (31%) asbestos-related diseases were diagnosed following ATS criteria (2004). Using nonparametric statistical methods (permutation tests) 6 variables were analyzed with respect to asbestos-related diseases and working sectors, demonstrating a difference in the concentration of amphiboles (p < 0.01), greater in patients with asbestosis and workers involved in asbestos removal from railway carriages. There was not a correlation between mesothelin and amphiboles, chrysotile and total fibers concentrations (Spearman test).
ISSN:1592-7830