A Frequent Toll-Like Receptor 1 Gene Polymorphism Affects NK- and T-cell IFN-γ Production and is Associated with Helicobacter pylori-induced Gastric Disease

Background Helicobacter pylori infects approximately 50% of the world population. Among the infected individuals, only 10–20% develop peptic ulcers and

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Helicobacter (Cambridge, Mass.) Mass.), 2013-02, Vol.18 (1), p.13-21
Hauptverfasser:	Yang, Chin-An, Scheibenbogen, Carmen, Bauer, Sandra, Kleinle, Christoph, Wex, Thomas, Bornschein, Jan, Malfertheiner, Peter, Hellmig, Stephan, Schumann, Ralf R., Hamann, Lutz
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Cytokines Female gamma -Interferon Gastric cancer Gastritis Gene polymorphism genetic susceptibility Genotype Guanylate cyclase Helicobacter Infections - immunology Helicobacter Infections - pathology Helicobacter pylori Helicobacter pylori - pathogenicity Helper cells Humans Immune response Inflammation Interferon-gamma - secretion Killer Cells, Natural - immunology Lymphocytes T Male Middle Aged Monocytes peptic ulcer peptic ulcers Polymorphism, Single Nucleotide Risk factors Risk groups Single-nucleotide polymorphism Stomach Diseases - immunology Stomach Diseases - pathology T-Lymphocytes - immunology TLR1 protein TLR2 protein Toll-Like Receptor 1 - genetics Toll-Like Receptor 1 - immunology Toll-like receptors Ulcers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Background Helicobacter pylori infects approximately 50% of the world population. Among the infected individuals, only 10–20% develop peptic ulcers and
ISSN:	1083-4389 1523-5378
DOI:	10.1111/hel.12001