Stress symptoms and health-related quality of life in patients after orthotopic liver transplantation

The study explored the presence of stress symptoms among orthotopic liver transplantation (OLT) recipients and investigated how stress symptoms are linked to health-related quality of life (HRQOL). A new concept of adjustment disorder as a stress response syndrome according to Maercker was considered. We recruited 76 OLT recipients, all of whom had been treated in the Department of Surgery, Division of Transplantation Surgery, University of Medicine of Graz, Austria. A self-rating scale was administered to evaluate stress symptoms (PTSS-10). The data on health-related quality of life were obtained from the SF-36 (Health Status Questionnaire). Following OLT 30.3 % (n = 23) of the sample suffered from stress symptoms. In the group of patients suffering from stress symptoms there were significant impairments in health related quality of life in the SF-36 health-related domains physical functioning, role physical, pain, general health, vitality, social functioning, role emotional, and mental health. OLT recipients may face a major risk of OLT-related postoperative stress symptoms in the sense of adjustment disorders according to Maercker. Stress symptoms are highly associated with impairments in quality of life.