Exact analysis of a paired sibling study

Exact analysis of a paired sibling study

A data set on types of congenital heart malformations for sibling pairs of Fraser and Hunter (1975) is analyzed exactly for quasi-independence with Monte Carlo methods. Exactp-values are computed for a test of parameter significance and a test of goodness-of-fit which contradict the model of quasiin...

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Veröffentlicht in:Computational statistics 2004-12, Vol.19 (4), p.525-534
Hauptverfasser: Dinwoodie, I. H., MacGibbon, Brenda
Format: Artikel
Sprache:eng
Schlagworte:
Applied mathematics
Computation
Computer simulation
Congenital diseases
Heart
Mathematical models
Monte Carlo methods
Monte Carlo simulation
Statistics
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Zusammenfassung:A data set on types of congenital heart malformations for sibling pairs of Fraser and Hunter (1975) is analyzed exactly for quasi-independence with Monte Carlo methods. Exactp-values are computed for a test of parameter significance and a test of goodness-of-fit which contradict the model of quasiindependence and confirm an earlier analysis of MacGibbon (1983).[PUBLICATION ABSTRACT]
ISSN:0943-4062
1613-9658
DOI:10.1007/BF02753910