A platform pathway for production of 3-hydroxyacids provides a biosynthetic route to 3-hydroxy-γ-butyrolactone

The replacement of petroleum feedstocks with biomass to produce platform chemicals requires the development of appropriate conversion technologies. 3-Hydroxy-γ-butyrolactone has been identified as one such chemical; however, there are no naturally occurring biosynthetic pathways for this molecule or...

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Veröffentlicht in:	Nature communications 2013-01, Vol.4 (1), p.1414-1414, Article 1414
Hauptverfasser:	Martin, Collin H., Dhamankar, Himanshu, Tseng, Hsien-Chung, Sheppard, Micah J., Reisch, Christopher R., Prather, Kristala L.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Butyrolactone - analogs & derivatives 4-Butyrolactone - biosynthesis 631/61/252/318 Biosynthetic Pathways - drug effects Biosynthetic Pathways - genetics Escherichia coli - drug effects Escherichia coli - enzymology Escherichia coli - metabolism Genes, Bacterial - genetics Glucose - metabolism Glycolates - metabolism Humanities and Social Sciences Hydrochloric Acid - pharmacology Hydroxy Acids - chemistry Hydroxy Acids - metabolism Isomerism Metabolomics multidisciplinary Recombination, Genetic - genetics Reproducibility of Results Science Science (multidisciplinary)
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