Proficiency testing matters
Even for central-laboratory techniques, traditional PT suffers from "matrix effects," in that samples used for testing often react differently from native patient samples. [...]comparisons must be made only to peer groups, rather than to the "true value" (11 ).What if the peer gr...
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Veröffentlicht in: | Clinical chemistry (Baltimore, Md.) Md.), 2013-02, Vol.59 (2), p.335-337 |
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Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Even for central-laboratory techniques, traditional PT suffers from "matrix effects," in that samples used for testing often react differently from native patient samples. [...]comparisons must be made only to peer groups, rather than to the "true value" (11 ).What if the peer group as a whole is wrong (12 )? [...]it is not clear that the bias, which is expressed in the report as a percentage, is constant across all concentrations of the measurand (15 ). |
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ISSN: | 0009-9147 1530-8561 |
DOI: | 10.1373/clinchem.2012.197574 |