Proficiency testing matters

Even for central-laboratory techniques, traditional PT suffers from "matrix effects," in that samples used for testing often react differently from native patient samples. [...]comparisons must be made only to peer groups, rather than to the "true value" (11 ).What if the peer gr...

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Veröffentlicht in:Clinical chemistry (Baltimore, Md.) Md.), 2013-02, Vol.59 (2), p.335-337
1. Verfasser: Horowitz, Gary L
Format: Artikel
Sprache:eng
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Zusammenfassung:Even for central-laboratory techniques, traditional PT suffers from "matrix effects," in that samples used for testing often react differently from native patient samples. [...]comparisons must be made only to peer groups, rather than to the "true value" (11 ).What if the peer group as a whole is wrong (12 )? [...]it is not clear that the bias, which is expressed in the report as a percentage, is constant across all concentrations of the measurand (15 ).
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2012.197574