Cardiopulmonary Variables During Exercise Predict Pregnancy Outcome in Women With Congenital Heart Disease

Background: Maternal New York Heart Association (NYHA) class is associated with pregnancy outcome in women with congenital heart disease (WCHD), but objective predictive criteria of exercise capacity have not been established. Methods and Results: A total of 33 WCHD (age, 28±5 years; NYHA class, 1.3...

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Veröffentlicht in:	Circulation Journal 2013, Vol.77(2), pp.470-476
Hauptverfasser:	Ohuchi, Hideo, Tanabe, Yuka, Kamiya, Chizuko, Noritake, Kanae, Yasuda, Kenji, Miyazaki, Aya, Ikeda, Tomoaki, Yamada, Osamu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arrhythmias, Cardiac - diagnosis Arrhythmias, Cardiac - physiopathology Birth weight Birth Weight - physiology Blood Pressure - physiology Congenital heart disease Exercise - physiology Exercise capacity Exercise Test Exercise Tolerance - physiology Female Heart Defects, Congenital - diagnosis Heart Defects, Congenital - epidemiology Heart Defects, Congenital - physiopathology Heart Rate - physiology Humans Infant, Newborn Oxygen Consumption - physiology Predictive Value of Tests Pregnancy Pregnancy Complications, Cardiovascular - diagnosis Pregnancy Complications, Cardiovascular - epidemiology Pregnancy Complications, Cardiovascular - physiopathology Pregnancy Outcome - epidemiology Prevalence Prognosis Retrospective Studies Young Adult
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Zusammenfassung:	Background: Maternal New York Heart Association (NYHA) class is associated with pregnancy outcome in women with congenital heart disease (WCHD), but objective predictive criteria of exercise capacity have not been established. Methods and Results: A total of 33 WCHD (age, 28±5 years; NYHA class, 1.3±0.6) who had undergone cardiopulmonary exercise testing (CPX) 1.8±2.2 years before their delivery were retrospectively identified. Maternal, cardiac, and neonatal events occurred in 8 (24%), 12 (36%), and 14 (42%), respectively. All CPX parameters correlated with neonatal birth weight (P
ISSN:	1346-9843 1347-4820
DOI:	10.1253/circj.CJ-12-0485