Peritoneal phosphate removal varies by peritoneal dialysis regimen: an underestimated parameter of phosphate control

The optimization of phosphate (P) removal by peritoneal dialysis (PD) is often underestimated. Our objective was to investigate peritoneal P clearance and its relationship with standard adequacy targets, hyperphosphatemia and automated PD (APD) parameters. Dialysis dose, P clearances (24-hour urine...

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Veröffentlicht in:	Journal of nephrology 2013-01, Vol.26 (1), p.183-190
Hauptverfasser:	Botelho, Carlos, Rodrigues, Anabela, Oliveira, Jose Carlos, Cabrita, António
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anuria - blood Anuria - complications Creatinine - blood Creatinine - metabolism Cross-Sectional Studies Female Humans Hyperphosphatemia - blood Hyperphosphatemia - etiology Male Membranes, Artificial Middle Aged Peritoneal Cavity Peritoneal Dialysis - methods Peritoneal Dialysis, Continuous Ambulatory Phosphates - blood Phosphates - metabolism Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - therapy Time Factors Ultrafiltration
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Zusammenfassung:	The optimization of phosphate (P) removal by peritoneal dialysis (PD) is often underestimated. Our objective was to investigate peritoneal P clearance and its relationship with standard adequacy targets, hyperphosphatemia and automated PD (APD) parameters. Dialysis dose, P clearances (24-hour urine and effluent samples), estimated percentage of diffusive P removal and peritoneal transport rate (PET) were evaluated in 77 adult prevalent PD patients. Total P removal strongly correlated with residual renal function parameters, dissociated from peritoneal Kt/V urea (r=-0.36; p=0.02) and creatinine clearance (r=-0.32; p
ISSN:	1121-8428 1724-6059
DOI:	10.5301/jn.5000109