Serum anti-Müllerian hormone levels are lower in reproductive-age women with Crohn's disease compared to healthy control women

Crohn’s disease (CD) decreases fertility both directly, by inducing inflammation in the fallopian tubes and ovaries, and indirectly, through the surgical interventions and tubal adhesions associated with disease treatment. Anti-müllerian hormone (AMH) is a reliable indicator of ovarian reserve in women. We aimed to compare serum AMH levels between reproductive-age women with CD and healthy controls. Serum AMH levels were measured by ELISA in 35 women with CD and 35 age-matched healthy women controls. CD patients and controls were similar in terms of age, height, weight and BMI. Mean CD duration was 60 months. CRP, ESR and leukocyte counts were significantly higher in CD patients compared to the controls (p