Deterioration of horizontal saccades in progressive supranuclear palsy

Highlights ► We studied horizontal saccade changes in progressive supranuclear palsy (PSP). ► This was compared with those of Parkinson’s disease (PD) at various disease stages. ► Amplitudes of saccades decreased with increasing disease stage in PSP, but not in PD. ► Deterioration of horizontal sacc...

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Veröffentlicht in:	Clinical neurophysiology 2013-02, Vol.124 (2), p.354-363
Hauptverfasser:	Terao, Yasuo, Fukuda, Hideki, Shirota, Yuichiro, Yugeta, Akihiro, Yoshioka, Masayuki, Suzuki, Masahiko, Hanajima, Ritsuko, Nomura, Yoshiko, Segawa, Masaya, Tsuji, Shoji, Ugawa, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Basal ganglia Biological and medical sciences Brain Stem - physiopathology Brainstem Case-Control Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Progression Electrodiagnosis. Electric activity recording Female Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Memory - physiology Middle Aged Nervous system Neurology Parkinson Disease - physiopathology Parkinson’s disease Progressive Saccades Saccades - physiology Superior colliculus Supranuclear palsy Supranuclear Palsy, Progressive - physiopathology Vision, Ocular - physiology
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Zusammenfassung:	Highlights ► We studied horizontal saccade changes in progressive supranuclear palsy (PSP). ► This was compared with those of Parkinson’s disease (PD) at various disease stages. ► Amplitudes of saccades decreased with increasing disease stage in PSP, but not in PD. ► Deterioration of horizontal saccades may be due to brainstem oculomotor pathology.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2012.07.008